Frequently Asked Questions

Q. How often should I take Zymosine?

The regular recommended dosage of Zymosine is 2 capsules 3 times a day. This can be increased to 3 capsules 3 times a day if needed. Also if taken for Osteoarthritis you may be able to reduce your dosage after 30 to 60 days to 1 capsule 3 times a day.

Q. How many capsules are in a bottle? How long does a bottle last?

There are 180 capsules in a bottle. Each serving contains 1,440mg active ingredients per serving. This is a 30 day supply at the regular recommended dosage.

Q. How do the ingredients in Zymosine compare to Anti-Inflammatory Pain Relievers?

Numerous clinical studies have been conducted on the pain relieving and anti-inflammatory effects of the ingredients in Zymosine and many of those studies compare the efficacy with OTC and prescription pain relievers. Most studies have focused on back pain, knee pain, hip pain and other joint pain. Ingredient comparisons have been done with:

  • Rofecoxib (Vioxx)
  • Etodolac (Lodine)
  • Indomethacin (Indocin)
  • Acetaminophen
  • Naproxen (Aleve, Naprosyn, Anaprox)
  • Piroxicam (Feldene)
  • Diclofenac (Cataflam, Voltaren, Arthrotec)
  • Diacerhein
  • Ibuprofen (Advil, Motrin)
  • Ketoprofen (Oruvail, Orudis, Actron)

The specific Zymosine ingredient compared in each study was better tolerated, had fewer side effects and had a pain relieving and/or anti-inflammatory effect equal to or greater than the comparable OTC or prescription anti-inflammatory pain reliever. (26,27, 28, 37, 38, 40, 56, 57, 65, 72, 80, 81, 82)

Also Zymosine contains ingredients which promote health, regeneration and healing of joints, spine and connective tissue. Pain relievers do not help the health of your joints spine or connective tissue.

Please Note: Results may vary depending on the individual, their medical condition and type of pain.  

Q. Are the ingredients in Zymosine safe?

All of the ingredients in Zymosine fall under the FDA's GRAS Standard (Generally Accepted As Safe) as well as significant research and review has been conducted on each ingredient. To date all of the ingredients have been reported to be safe and well tolerated in studies. (Please See Precautions).

We us pharmacy grade herbal extracts to provide the greatest purity, consistency and potency. The raw ingredients and the final product is test and analyzed to insure safety, purity and formulation.

Zymosine is manufactured in the United States in FDA Certified Facilities in accordance with cGMP standards.

Q. I am allergic to sulfur drugs is it OK to take Zymosine?

Yes. Zymosine should be not pose a problem.

Thatís a very common question. When people are allergic to sulfur drugs they are generally referring to the sulfasalazine that is in Bactrim or Septra. That is different than the kind of conjugated sulfate group that is found in our product (and in most of the food that you eat.)

The sulfur in Zymosine is similar to the sulfur in food which is an essential element in your body that you cannot live without.

Q. I am allergic to Aspirin is it OK to take Zymosine?

Yes, it is OK to take Zymosine.

There are no reports or studies that we are aware of indicating any allergic reactions for individuals with an aspirin allergy.

For your reference if you have an aspirin allergy your should avoid the following herbal supplement ingredients (NONE of these are in Zymosine): meadowsweet, white willow tree (Salix alba), crack willow (Salix fragilis), purple willow (Salix purpurea), and violet willow (Salix daphnoides). white willow is the most commonly used of the above herbal pain supplements.

Those plants contain salicin which is converted in the body to salicylic acid which is almost identical chemically to aspirin and should be avoided by anyone with an aspirin allergy.

Q. Are there any precautions?

As with all supplements and foods, allergic reactions could occur. If you have a known allergic reaction to pineapple the ingredient Bromelain (made form pineapple) may cause an allergic reaction.

Adverse reactions could occur with any supplement or drug. We recommend that you always discuss the use of any supplement with your health care professional.

As with the majority of supplements, studies regarding the effect on fetal and nursing babies are limited so we do not recommend it's use by pregnant or nursing women.

Q. Are there any side effects?

Studies that have been conducted on the ingredients in Zymosine report that they are well tolerated in individuals and have few if any minor side effects. Patient studies conducted comparing the herbal ingredients in Zymosine with other pain relievers have reported fewer patient side-effects than OTC or prescription pain relievers.

Q. How should I store Zymosine?

You should store Zymosine in a cool location out of direct sunlight.

Q. What is your guarantee?

Your satisfaction with Zymosine is 100% unconditionally guaranteed for a full 90 days. If for any reason or no reason you are not 100% satisfied, simply return the empty and any remaining bottles and we will promptly refund 100% of product cost. Please note: shipping & handling is not refunded.


View Research References 27,37,38,40,56,80,81,82


Claims made on this site have not been evaluated by the United States Food and Drug Administration and are for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional. This product is not intended to diagnose, treat, cure or prevent disease. Zymosine is a trademark of Boulder Natural Labs, LLC.

© 2004 Boulder Natural Labs, LLC. All rights reserved.